Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Cathepsin L Inhibitor I
The Cathepsin L Inhibitor I, also referenced under CAS 108005-94-3, controls the biological activity of Cathepsin L. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ MMP-13 Inhibitor
The MMP-13 Inhibitor, also referenced under CAS 544678-85-5, controls the biological activity of MMP-13. This small molecule/inhibitor is primarily used for Protease Inhibitors applications.
MilliporeSigma™ Calbiochem™ BEC, Hydrochloride
A boronic acid-based arginine analog that acts as a slow-binding, competitive transition state inhibitor of arginases I and II (Ki = 310 nM for human recombinant type II arginase, pH 7.5).
MilliporeSigma™ Calbiochem™ Eg5 Inhibitor III, Dimethylenastron
The Eg5 Inhibitor III, Dimethylenastron, also referenced under CAS 863774-58-7, controls the biological activity of Eg5. This small molecule/inhibitor is primarily used for Membrane applications.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor VI
Z-VAD-FMK, CAS 161401-82-7, is an irreversible pan caspase inhibitor. Does not require pretreatment with esterase for in vitro studies.
MilliporeSigma™ Calbiochem™ Necrostatin-1, Inactive Control
A cell-permeable N-demethylated thiohydantoin analog of Nec-1 that is devoid of anti-necroptotic properties and serves as a suitable inactive control.
MilliporeSigma™ Calbiochem™ SKP2 E3 Ligase Inhibitor I, C1
A cell-permeable rhodanine compound that upregulates cellular p21Cip1/Waf1 and p27Kip1 protein levels (10μM for 16 h in 501 Mel cultures) by preventing Skp2-Cks1-mediated substrate recruitment without affecting the F-box E3 ubiquitin ligase Skp2 interaction with Cks1 or the SCF (Skp1-cullin1-F-box) c
MilliporeSigma™ Calbiochem™ LRRK2 Inhibitor II, CZC-25146
The LRRK2 Inhibitor II, CZC-25146 controls the biological activity of LRRK2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Histone Deacetylase Inhibitor VII, 106
The Histone Deacetylase Inhibitor VII, 106, also referenced under CAS 937039-45-7, controls the biological activity of Histone Deacetylase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Caspase-1 Substrate VI, Fluorogenic
Fluorogenic caspase-1 substrate.
MilliporeSigma™ Calbiochem™ InSolution™ Casein Kinase II Inhibitor III, TBCA
The InSolution™ Casein Kinase II Inhibitor III, TBCA, also referenced under CAS 934358-00-6, controls the biological activity of Casein Kinase II. This small molecule/inhibitor is primarily used for Phosphorylation and Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Luciferase Inhibitor II
The Luciferase Inhibitor II, also referenced under CAS 10205-56-8, controls the biological activity of Luciferase.
MilliporeSigma™ Calbiochem™ HIF-PHD Inhibitor II, JNJ-42041935
The HIF-PHD Inhibitor II, JNJ-42041935 controls the biological activity of HIF-PHD. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ P-Glycoprotein Inhibitor, C-4
The P-Glycoprotein Inhibitor, C-4 controls the biological activity of P-Glycoprotein. This small molecule/inhibitor is primarily used for Cancer applications.