Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ Wortmannin
Wortmannin, CAS 19545-26-7, is a cell-permeable, potent, selective, and irreversible inhibitor of PI3-Kinase (IC50 = 5 nM). Does not affect any upstream signaling events.
MilliporeSigma™ Calbiochem™ InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2
The InSolution™ Akt Inhibitor VIII, Isozyme-Selective, Akti-1/2 controls the biological activity of Akt.
MilliporeSigma™ Calbiochem™ PICK1 PDZ Domain Inhibitor, FSC231
The PICK1 PDZ Domain Inhibitor, FSC231 controls the biological activity of PICK1. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Thapsigargin
Thapsigargin, CAS 67526-95-8, is a cell-permeable, tumor-promoting sesquiterpene lactone that releases calcium by non-competitvley inhibiting endoplasmic reticular Ca2+-ATPase (IC50 = 4-13 nM).
MilliporeSigma™ Calbiochem™ Castanospermine, Castanospermum australe
Plant alkaloid inhibitor of several β-glucosidases and α-glucosidases, including those involved in N-linked processing of glycoproteins.
MilliporeSigma™ Calbiochem™ Methysergide Maleate
An antagonist of the 5-HT2B (pki
MilliporeSigma™ Calbiochem™ TLR3/dsRNA Complex Inhibitor
The TLR3/dsRNA Complex Inhibitor blocks dsRNA binding to TLR3.
MilliporeSigma™ Calbiochem™ HIF Inhibitor V
A cell-permeable phenoxyacrylamido compound that inhibits hypoxia-induced cellular HIF-1α accumulation in a manner similar to LW6 (Cat
MilliporeSigma™ Calbiochem™ γ-Secretase Inhibitor VI
The γ-Secretase Inhibitor VI, also referenced under CAS 287196-57-0, controls the biological activity of γ-Secretase. This small molecule/inhibitor is primarily used for Neuroscience applications.
MilliporeSigma™ Calbiochem™ Piperlongumine
A cell-permeable, orally bioavailable natural product isolated from the plant species, Piper longum L, which selectively induces cell death in cancer cells that express both wild-type and mutant p53.
MilliporeSigma™ Calbiochem™ MRP1 Inhibitor II, Reversan
The MRP1 Inhibitor II, Reversan controls the biological activity of MRP1. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ PKCθ Pseudosubstrate Inhibitor, Myristoylated
The PKCθ Pseudosubstrate Inhibitor, Myristoylated controls the biological activity of PKCθ. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Caspase Inhibitor I, Biotin Conjugate
The Caspase Inhibitor I, Biotin Conjugate controls the biological activity of Caspase. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ JNK Inhibitor II
The InSolution™ JNK Inhibitor II, also referenced under CAS 129-56-6, controls the biological activity of JNK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.